Effectiveness of Vaccination Strategies for Infectious Diseases According to Human Contact Networks
Identifieur interne : 004C20 ( Main/Exploration ); précédent : 004C19; suivant : 004C21Effectiveness of Vaccination Strategies for Infectious Diseases According to Human Contact Networks
Auteurs : Fumihiko Takeuchi [Japon, Namibie] ; Kenji Yamamoto [Japon]Source :
- Lecture Notes in Computer Science [ 0302-9743 ]
Abstract
Abstract: A ‘contact network’ modeling infection transmission comprises of nodes (or individuals) that are linked when they are in contact that possibly transmits an infection. We here studied infection transmission on contact networks of various degree distributions—scale-free, exponential and constant—under SIRV model assuming susceptible, infected, removed and vaccinated statuses of nodes. Aiming for infectious disease containment within the very early stage of spreading, we computed the minimum transmissibility at which an infectious disease epidemic begins to emerge, and its change according to mass preventive and ring post-outbreak vaccination. In the most degree-heterogeneous scale-free network, the ‘super-spreading’ by the hubs, or high-degree nodes, allowed epidemics even for low transmissibility. In compensation, vaccination was much more efficient for the scale-free network. We also found that basic reproductive number R 0 defines a measurement of epidemic emergence universally applicable to networks of various degree distributions. These results are significant for public health design.
Url:
DOI: 10.1007/11428831_119
Affiliations:
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We here studied infection transmission on contact networks of various degree distributions—scale-free, exponential and constant—under SIRV model assuming susceptible, infected, removed and vaccinated statuses of nodes. Aiming for infectious disease containment within the very early stage of spreading, we computed the minimum transmissibility at which an infectious disease epidemic begins to emerge, and its change according to mass preventive and ring post-outbreak vaccination. In the most degree-heterogeneous scale-free network, the ‘super-spreading’ by the hubs, or high-degree nodes, allowed epidemics even for low transmissibility. In compensation, vaccination was much more efficient for the scale-free network. We also found that basic reproductive number R 0 defines a measurement of epidemic emergence universally applicable to networks of various degree distributions. These results are significant for public health design.</div></front></TEI><affiliations><list><country><li>Japon</li><li>Namibie</li></country><region><li>Région de Kantō</li></region><settlement><li>Tokyo</li></settlement></list><tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Takeuchi, Fumihiko" sort="Takeuchi, Fumihiko" uniqKey="Takeuchi F" first="Fumihiko" last="Takeuchi">Fumihiko Takeuchi</name></region><name sortKey="Takeuchi, Fumihiko" sort="Takeuchi, Fumihiko" uniqKey="Takeuchi F" first="Fumihiko" last="Takeuchi">Fumihiko Takeuchi</name><name sortKey="Yamamoto, Kenji" sort="Yamamoto, Kenji" uniqKey="Yamamoto K" first="Kenji" last="Yamamoto">Kenji Yamamoto</name><name sortKey="Yamamoto, Kenji" sort="Yamamoto, Kenji" uniqKey="Yamamoto K" first="Kenji" last="Yamamoto">Kenji Yamamoto</name></country><country name="Namibie"><noRegion><name sortKey="Takeuchi, Fumihiko" sort="Takeuchi, Fumihiko" uniqKey="Takeuchi F" first="Fumihiko" last="Takeuchi">Fumihiko Takeuchi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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